NGS – Next-Generation Sequencing
NGS, next-generation sequencing, is a laboratory method that reads genetic material from cells taken from an embryo. The treatment decision is not made by the machine. It is made when a physician interprets the result.
What NGS adds to embryo testing
Some preimplantation genetic tests run on this technology. The aim is to produce laboratory data on chromosome number and on the genetic regions being asked about. NGS can read more of a small sample than older methods. The output is still a report. Which embryo is transferred is discussed together with the clinical findings.
Is NGS the same as PGT?
- NGS is the laboratory method. PGT is the clinical test that may use it
- Not every embryo needs NGS. The test is planned when there is a reason
- The method does not guarantee a pregnancy or make an embryo implant
- Mosaic or borderline results may need further counselling
How the path usually unfolds
- Genetic counselling and a clear reason for the test
- IVF until an embryo reaches the stage suitable for biopsy
- The biopsy sample is examined by NGS
- The report is read with the physician and a transfer decision is made
This page describes the laboratory method. The clinical test types are summarised on the preimplantation genetic testing page. Results are interpreted with genetic counselling and a physician.
IVF
Egg Donation
Tandem Treatment
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