Preimplantation Genetic Testing
Preimplantation genetic testing examines an embryo before it is transferred to the uterus. Older texts call this PGD. Today these tests are grouped under the name PGT.
What PGT looks at
The type of test follows the question being asked. PGT-A looks at the number of chromosomes. PGT-M targets a known single-gene condition in the family. PGT-SR looks at a break or rearrangement in chromosome structure. Sex chromosomes may appear in the report. That does not mean every country allows sex selection.
Who may consider it?
- Repeated pregnancy loss, or repeated IVF without a pregnancy
- A known single-gene condition in a prospective parent
- A structural difference in the chromosome arrangement
- Later reproductive age, when extra information on chromosome number is requested
How the path usually unfolds
- Genetic counselling and a choice of which test is actually needed
- IVF to create embryos
- A biopsy from the embryo and laboratory testing
- After the report, a decision on which embryo to transfer
The test does not promise a healthy child. A biopsy is a limited sample of the embryo. The laboratory method is described on the NGS page. Interpretation is done with genetic counselling and a physician.
IVF
Egg Donation
Tandem Treatment
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